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Regulatory B Cells (B10 cells) and Regulatory T Cells Have Independent Roles in Controlling EAE Initiation and Late-Phase Immunopathogenesis

Experimental autoimmune encephalomyelitis (EAE) is a T lymphocyte-mediated autoimmune disease of the CNS. Significant roles for B cells and a rare IL-10-producing CD1d(hi)CD5(+) regulatory B cell subset (B10 cells) have been identified during the initiation and progression of EAE. Whether and how th...

詳細記述

保存先:
書誌詳細
主要な著者: Matsushita, Takashi, Horikawa, Mayuka, Iwata, Yohei, Tedder, Thomas F.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717968/
https://ncbi.nlm.nih.gov/pubmed/20624940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001307
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