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Manifestation of Huntington’s disease pathology in human induced pluripotent stem cell-derived neurons
BACKGROUND: Huntington’s disease (HD) is an incurable hereditary neurodegenerative disorder, which manifests itself as a loss of GABAergic medium spiny (GABA MS) neurons in the striatum and caused by an expansion of the CAG repeat in exon 1 of the huntingtin gene. There is no cure for HD, existing p...
में बचाया:
| में प्रकाशित: | Mol Neurodegener |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4832474/ https://ncbi.nlm.nih.gov/pubmed/27080129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0092-5 |
| टैग : |
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