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Manifestation of Huntington’s disease pathology in human induced pluripotent stem cell-derived neurons

BACKGROUND: Huntington’s disease (HD) is an incurable hereditary neurodegenerative disorder, which manifests itself as a loss of GABAergic medium spiny (GABA MS) neurons in the striatum and caused by an expansion of the CAG repeat in exon 1 of the huntingtin gene. There is no cure for HD, existing p...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Neurodegener
मुख्य लेखकों: Nekrasov, Evgeny D., Vigont, Vladimir A., Klyushnikov, Sergey A., Lebedeva, Olga S., Vassina, Ekaterina M., Bogomazova, Alexandra N., Chestkov, Ilya V., Semashko, Tatiana A., Kiseleva, Elena, Suldina, Lyubov A., Bobrovsky, Pavel A., Zimina, Olga A., Ryazantseva, Maria A., Skopin, Anton Yu., Illarioshkin, Sergey N., Kaznacheyeva, Elena V., Lagarkova, Maria A., Kiselev, Sergey L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832474/
https://ncbi.nlm.nih.gov/pubmed/27080129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0092-5
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