GacA is essential for Group A S treptococcus and defines a new class of monomeric dTDP‐4‐dehydrorhamnose reductases (RmlD)

The sugar nucleotide dTDP‐L‐rhamnose is critical for the biosynthesis of the Group A Carbohydrate, the molecular signature and virulence determinant of the human pathogen Group A S treptococcus (GAS). The final step of the four‐step dTDP‐L‐rhamnose biosynthesis pathway is catalyzed by dTDP‐4‐dehydro...

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Detalles Bibliográficos
Publicado en:Mol Microbiol
Main Authors: van der Beek, Samantha L., Le Breton, Yoann, Ferenbach, Andrew T., Chapman, Robert N., van Aalten, Daan M. F., Navratilova, Iva, Boons, Geert‐Jan, McIver, Kevin S., van Sorge, Nina M., Dorfmueller, Helge C.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832382/
https://ncbi.nlm.nih.gov/pubmed/26278404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13169
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