GacA is essential for Group A S treptococcus and defines a new class of monomeric dTDP‐4‐dehydrorhamnose reductases (RmlD)

The sugar nucleotide dTDP‐L‐rhamnose is critical for the biosynthesis of the Group A Carbohydrate, the molecular signature and virulence determinant of the human pathogen Group A S treptococcus (GAS). The final step of the four‐step dTDP‐L‐rhamnose biosynthesis pathway is catalyzed by dTDP‐4‐dehydro...

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Foilsithe in:Mol Microbiol
Main Authors: van der Beek, Samantha L., Le Breton, Yoann, Ferenbach, Andrew T., Chapman, Robert N., van Aalten, Daan M. F., Navratilova, Iva, Boons, Geert‐Jan, McIver, Kevin S., van Sorge, Nina M., Dorfmueller, Helge C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2015
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832382/
https://ncbi.nlm.nih.gov/pubmed/26278404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13169
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