GacA is essential for Group A S treptococcus and defines a new class of monomeric dTDP‐4‐dehydrorhamnose reductases (RmlD)

The sugar nucleotide dTDP‐L‐rhamnose is critical for the biosynthesis of the Group A Carbohydrate, the molecular signature and virulence determinant of the human pathogen Group A S treptococcus (GAS). The final step of the four‐step dTDP‐L‐rhamnose biosynthesis pathway is catalyzed by dTDP‐4‐dehydro...

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Dettagli Bibliografici
Pubblicato in:Mol Microbiol
Autori principali: van der Beek, Samantha L., Le Breton, Yoann, Ferenbach, Andrew T., Chapman, Robert N., van Aalten, Daan M. F., Navratilova, Iva, Boons, Geert‐Jan, McIver, Kevin S., van Sorge, Nina M., Dorfmueller, Helge C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832382/
https://ncbi.nlm.nih.gov/pubmed/26278404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13169
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