Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type

Small cell carcinoma of the ovary, hypercalcaemic type (SCCOHT) is a lethal and sometimes familial ovarian tumour of young women and children. We and others recently discovered that over 90% of SCCOHTs harbour inactivating mutations in the chromatin remodelling gene SMARCA4 with concomitant loss of...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Pathol
Main Authors: Karnezis, Anthony N, Wang, Yemin, Ramos, Pilar, Hendricks, William PD, Oliva, Esther, D'Angelo, Emanuela, Prat, Jaime, Nucci, Marisa R, Nielsen, Torsten O, Chow, Christine, Leung, Samuel, Kommoss, Friedrich, Kommoss, Stefan, Silva, Annacarolina, Ronnett, Brigitte M, Rabban, Joseph T, Bowtell, David D, Weissman, Bernard E, Trent, Jeffrey M, Gilks, C Blake, Huntsman, David G
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Original Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832362/
https://ncbi.nlm.nih.gov/pubmed/26356327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4633
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki