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Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods

Mendelian randomization is the use of genetic instrumental variables to obtain causal inferences from observational data. Two recent developments for combining information on multiple uncorrelated instrumental variables (IVs) into a single causal estimate are as follows: (i) allele scores, in which...

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書目詳細資料
發表在:Stat Med
Main Authors: Burgess, Stephen, Dudbridge, Frank, Thompson, Simon G.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832315/
https://ncbi.nlm.nih.gov/pubmed/26661904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6835
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