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Titin stiffness modifies the force-generating region of muscle sarcomeres

The contractile units of striated muscle, the sarcomeres, comprise the thick (myosin) and thin (actin) filaments mediating active contraction and the titin filaments determining “passive” elasticity. We hypothesized that titin may be more active in muscle contraction by directly modulating thick-fil...

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Publicado en:Sci Rep
Autores principales: Li, Yong, Lang, Patrick, Linke, Wolfgang A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832248/
https://ncbi.nlm.nih.gov/pubmed/27079135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24492
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