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Titin stiffness modifies the force-generating region of muscle sarcomeres

The contractile units of striated muscle, the sarcomeres, comprise the thick (myosin) and thin (actin) filaments mediating active contraction and the titin filaments determining “passive” elasticity. We hypothesized that titin may be more active in muscle contraction by directly modulating thick-fil...

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Publicat a:Sci Rep
Autors principals: Li, Yong, Lang, Patrick, Linke, Wolfgang A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832248/
https://ncbi.nlm.nih.gov/pubmed/27079135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24492
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