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Overexpression of Forebrain CRH During Early Life Increases Trauma Susceptibility in Adulthood

Although early-life stress is a significant risk factor for developing anxiety disorders, including posttraumatic stress disorder (PTSD), the underlying mechanisms are unclear. Corticotropin releasing hormone (CRH) is disrupted in individuals with PTSD and early-life stress and hence may mediate the...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Toth, Mate, Flandreau, Elizabeth I, Deslauriers, Jessica, Geyer, Mark A, Mansuy, Isabelle M, Merlo Pich, Emilio, Risbrough, Victoria B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832031/
https://ncbi.nlm.nih.gov/pubmed/26538448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.338
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