COMTval158met polymorphism links to altered fear conditioning and extinction are modulated by PTSD and childhood trauma

BACKGROUND: Risk for posttraumatic stress disorder (PTSD) is thought to be mediated by gene × environment (G×E) interactions that affect core cognitive processes such as fear learning. The catechol-O-methyltransferase (COMT) val158met polymorphism has been associated with risk for PTSD and impaired...

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Veröffentlicht in:Depress Anxiety
Hauptverfasser: Deslauriers, Jessica, Acheson, Dean T, Maihofer, Adam X, Nievergelt, Caroline M, Baker, Dewleen G, Geyer, Mark A, Risbrough, Victoria
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760328/
https://ncbi.nlm.nih.gov/pubmed/28833952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/da.22678
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