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Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line

Self-renewing organs often experience a decline in function in the course of aging. It is unclear whether chronological age or external factors control this decline, or whether it is driven by stem cell self-renewal—for example, because cycling cells exhaust their replicative capacity and become sen...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Cinquin, Amanda, Chiang, Michael, Paz, Adrian, Hallman, Sam, Yuan, Oliver, Vysniauskaite, Indre, Fowlkes, Charless C., Cinquin, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831802/
https://ncbi.nlm.nih.gov/pubmed/27077385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005985
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