Control of Caenorhabditis elegans germ-line stem-cell cycling speed meets requirements of design to minimize mutation accumulation

BACKGROUND: Stem cells are thought to play a critical role in minimizing the accumulation of mutations, but it is not clear which strategies they follow to fulfill that performance objective. Slow cycling of stem cells provides a simple strategy that can minimize cell pedigree depth and thereby mini...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Biol
Egile Nagusiak: Chiang, Michael, Cinquin, Amanda, Paz, Adrian, Meeds, Edward, Price, Christopher A., Welling, Max, Cinquin, Olivier
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538916/
https://ncbi.nlm.nih.gov/pubmed/26187634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0148-y
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