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Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line
Self-renewing organs often experience a decline in function in the course of aging. It is unclear whether chronological age or external factors control this decline, or whether it is driven by stem cell self-renewal—for example, because cycling cells exhaust their replicative capacity and become sen...
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| Publicat a: | PLoS Genet |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4831802/ https://ncbi.nlm.nih.gov/pubmed/27077385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005985 |
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