Progressive Axonal Degeneration of Nigrostriatal Dopaminergic Neurons in Calcium-Independent Phospholipase A(2)β Knockout Mice

Calcium-independent phospholipase A(2)β (iPLA(2)β, PLA2G6) is essential for the remodeling of membrane glycerophospholipids. Mutations in this gene are responsible for autosomal recessive, young onset, L-dopa-responsive parkinsonism (PARK14), suggesting a neurodegenerative condition in the nigrostri...

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發表在:PLoS One
Main Authors: Beck, Goichi, Shinzawa, Koei, Hayakawa, Hideki, Baba, Kousuke, Sumi-Akamaru, Hisae, Tsujimoto, Yoshihide, Mochizuki, Hideki
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831782/
https://ncbi.nlm.nih.gov/pubmed/27078024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153789
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