Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1

Mutations in PLA2G6 have been proposed to be the cause of neurodegeneration with brain iron accumulation type 2. The present study aimed to clarify the mechanism underlying brain iron accumulation during the deficiency of calcium-independent phospholipase A2 beta (iPLA(2)β), which is encoded by the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Beck, Goichi, Shinzawa, Koei, Hayakawa, Hideki, Baba, Kousuke, Yasuda, Toru, Sumi-Akamaru, Hisae, Tsujimoto, Yoshihide, Mochizuki, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624760/
https://ncbi.nlm.nih.gov/pubmed/26506412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141629
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