High expression of α-synuclein in damaged mitochondria with PLA2G6 dysfunction

To clarify the role of α-synuclein (αSyn) in neuronal membrane remodeling, we analyzed the expression of αSyn in neurons with a dysfunction of PLA2G6, which is indispensable for membrane remodeling. αSyn/phosphorylated-αSyn (PαSyn) distribution and neurodegeneration were quantitatively estimated in...

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Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Sumi-Akamaru, Hisae, Beck, Goichi, Shinzawa, Koei, Kato, Shinsuke, Riku, Yuichi, Yoshida, Mari, Fujimura, Harutoshi, Tsujimoto, Yoshihide, Sakoda, Saburo, Mochizuki, Hideki
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815115/
https://ncbi.nlm.nih.gov/pubmed/27030050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0298-3
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