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Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif

Quasiracemic crystallography has been used to explore the significance of homochiral and heterochiral associations in a set of host-defense peptide derivatives. The previously reported racemic crystal structure of a magainin 2 derivative displayed a homochiral dimer association featuring a “phenylal...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Hayouka, Zvi, Thomas, Nicole C., Mortenson, David E., Satyshur, Kenneth A., Weisblum, Bernard, Forest, Katrina T., Gellman, Samuel H.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831726/
https://ncbi.nlm.nih.gov/pubmed/26369301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b07206
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