Caricamento...
In vitro studies in a myelogenous leukemia cell line suggest an organized binding of geranylgeranyl diphosphate synthase inhibitors
A small set of isoprenoid bisphosphonates ethers have been tested in the K562 chronic myelogenous leukemia cell line to determine their impact on isoprenoid biosynthesis. Five of these compounds inhibit geranylgeranyl diphosphate synthase (GGDPS) with IC(50) values below 1 μM in enzyme assays, but i...
Salvato in:
| Pubblicato in: | Biochem Pharmacol |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4831703/ https://ncbi.nlm.nih.gov/pubmed/25952057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.04.009 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|