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Angiotensin type 1 receptor mediates renal production and conversion of prostaglandins E(2) to F(2)α in conscious diabetic rats

INTRODUCTION: Previous studies demonstrated that stimulation of angiotensin subtype 1 receptor (AT(1)R) led to increased renal generation of prostaglandins E(2) (PGE(2)) and renal inflammation. In turn, PGE(2) increases AT(1)R activity. The conversion of PGE(2) to the less active metabolite prostagl...

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Detalhes bibliográficos
Publicado no:J Renin Angiotensin Aldosterone Syst
Main Authors: Abadir, Peter M, Siragy, Helmy M
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831567/
https://ncbi.nlm.nih.gov/pubmed/26195268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1470320315592566
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