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Angiotensin type 1 receptor mediates renal production and conversion of prostaglandins E(2) to F(2)α in conscious diabetic rats
INTRODUCTION: Previous studies demonstrated that stimulation of angiotensin subtype 1 receptor (AT(1)R) led to increased renal generation of prostaglandins E(2) (PGE(2)) and renal inflammation. In turn, PGE(2) increases AT(1)R activity. The conversion of PGE(2) to the less active metabolite prostagl...
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| Udgivet i: | J Renin Angiotensin Aldosterone Syst |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4831567/ https://ncbi.nlm.nih.gov/pubmed/26195268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1470320315592566 |
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