Regulation of renal 12(S)-hydroxyeicosatetraenoic acid in diabetes by angiotensin AT(1) and AT(2) receptors

Diabetes is associated with increased production of 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE]. The mechanisms involved in this process remain unclear. We hypothesized that hyperglycemia and angiotensin II (ANG II) regulate renal 12(S)-HETE production via a balance between angiotensin AT(1) and...

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Main Authors: Abdel-Rahman, Emaad M., Abadir, Peter M., Siragy, Helmy M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2008
Assuntos:
Translational Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584863/
https://ncbi.nlm.nih.gov/pubmed/18799632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90699.2008
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