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Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT(1) receptor and NADPH oxidase activity

Recent studies have demonstrated the presence of the (pro)renin receptor (PRR) in the glomerular mesangium and the subendothelial layer of the renal arteries. We hypothesized that diabetes upregulates PRR expression through enhanced angiotensin subtype 1 (AT(1)) receptor–NADPH oxidase cascade activi...

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Bibliografische gegevens
Hoofdauteurs: Siragy, Helmy M., Huang, Jiqian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586037/
https://ncbi.nlm.nih.gov/pubmed/18192338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2007.040550
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