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SODIUM DEPLETION ENHANCES RENAL EXPRESSION OF (PRO)RENIN RECEPTOR VIA cGMP-PKG SIGNALING PATHWAY

(Pro)renin receptor (PRR) is expressed in renal vasculature, glomeruli and tubules. The physiologic regulation of this receptor is not well established. We hypothesized that sodium depletion increases PRR expression through cGMP-PKG signaling pathway. Renal PRR expressions were evaluated in Sprague-...

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Detalhes bibliográficos
Main Authors: Huang, Jiqian, Siragy, Helmy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266459/
https://ncbi.nlm.nih.gov/pubmed/22203739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.186056
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