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Hippocampal 5‐HT(7) receptors signal phosphorylation of the GluA1 subunit to facilitate AMPA receptor mediated‐neurotransmission in vitro and in vivo

BACKGROUND AND PURPOSE: The 5‐HT(7) receptor is a GPCR that is the target of a broad range of antidepressant and antipsychotic drugs. Various studies have demonstrated an ability of the 5‐HT(7) receptor to modulate glutamatergic neurotransmission and cognitive processes although the potential impact...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Andreetta, Filippo, Carboni, Lucia, Grafton, Gillian, Jeggo, Ross, Whyment, Andrew D, van den Top, Marco, Hoyer, Daniel, Spanswick, David, Barnes, Nicholas M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831309/
https://ncbi.nlm.nih.gov/pubmed/26773257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13432
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