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d‐Penicillamine modulates hydrogen sulfide (H(2)S) pathway through selective inhibition of cystathionine‐γ‐lyase
BACKGROUND AND PURPOSE: Hydrogen sulfide (H(2)S) is a gasotransmitter produced from l‐cysteine through the enzymatic action of cystathionine‐γ‐lyase (CSE) and/or cystathionine‐β‐synthase. d‐Penicillamine is the d isomer of a dimethylated cysteine and has been used for the treatment of rheumatoid art...
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| Publicado no: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4831308/ https://ncbi.nlm.nih.gov/pubmed/26890936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13459 |
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