d‐Penicillamine modulates hydrogen sulfide (H(2)S) pathway through selective inhibition of cystathionine‐γ‐lyase

BACKGROUND AND PURPOSE: Hydrogen sulfide (H(2)S) is a gasotransmitter produced from l‐cysteine through the enzymatic action of cystathionine‐γ‐lyase (CSE) and/or cystathionine‐β‐synthase. d‐Penicillamine is the d isomer of a dimethylated cysteine and has been used for the treatment of rheumatoid art...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Brancaleone, Vincenzo, Esposito, Iolanda, Gargiulo, Antonella, Vellecco, Valentina, Asimakopoulou, Antonia, Citi, Valentina, Calderone, Vincenzo, Gobbetti, Thomas, Perretti, Mauro, Papapetropoulos, Andreas, Bucci, Mariarosaria, Cirino, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831308/
https://ncbi.nlm.nih.gov/pubmed/26890936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13459
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