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Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide
Soluble guanylate cyclase (sGC) is a receptor for nitric oxide (NO). Binding of NO to ferrous (Fe(2+)) heme increases its catalytic activity, leading to the production of cGMP from GTP. Hydrogen sulfide (H(2)S) is a signalling molecule that exerts both direct and indirect anti-oxidant effects. In th...
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| Publicado no: | Pharmacol Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5130351/ https://ncbi.nlm.nih.gov/pubmed/27378567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.06.029 |
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