Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide

Soluble guanylate cyclase (sGC) is a receptor for nitric oxide (NO). Binding of NO to ferrous (Fe(2+)) heme increases its catalytic activity, leading to the production of cGMP from GTP. Hydrogen sulfide (H(2)S) is a signalling molecule that exerts both direct and indirect anti-oxidant effects. In th...

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Bibliografische gegevens
Gepubliceerd in:Pharmacol Res
Hoofdauteurs: Zhou, Zongmin, Martin, Emil, Sharina, Iraida, Esposito, Iolanda, Szabo, Csaba, Bucci, Mariarosaria, Cirino, Giuseppe, Papapetropoulos, Andreas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130351/
https://ncbi.nlm.nih.gov/pubmed/27378567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.06.029
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