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Immunogenicity of Leishmania-derived hepatitis B small surface antigen particles exposing highly conserved E2 epitope of hepatitis C virus

BACKGROUND: Hepatitis C virus (HCV) infection is a major health problem worldwide, affecting an estimated 2–3 % of human population. An HCV vaccine, however, remains unavailable. High viral diversity poses a challenge in developing a vaccine capable of eliciting a broad neutralizing antibody respons...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Czarnota, Anna, Tyborowska, Jolanta, Peszyńska-Sularz, Grażyna, Gromadzka, Beata, Bieńkowska-Szewczyk, Krystyna, Grzyb, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831159/
https://ncbi.nlm.nih.gov/pubmed/27075377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0460-4
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