The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity.

The nucleocapsid (HBcAg) of the hepatitis B virus (HBV) has been suggested as a carrier moiety for vaccine purposes. We investigated the influence of the position of the inserted epitope within hybrid HBcAg particles on antigenicity and immunogenicity. For this purpose, genes coding for neutralizing...

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Detalhes bibliográficos
Main Authors: Schödel, F, Moriarty, A M, Peterson, D L, Zheng, J A, Hughes, J L, Will, H, Leturcq, D J, McGee, J S, Milich, D R
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC238265/
https://ncbi.nlm.nih.gov/pubmed/1370083
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