The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity.

The nucleocapsid (HBcAg) of the hepatitis B virus (HBV) has been suggested as a carrier moiety for vaccine purposes. We investigated the influence of the position of the inserted epitope within hybrid HBcAg particles on antigenicity and immunogenicity. For this purpose, genes coding for neutralizing...

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Détails bibliographiques
Auteurs principaux: Schödel, F, Moriarty, A M, Peterson, D L, Zheng, J A, Hughes, J L, Will, H, Leturcq, D J, McGee, J S, Milich, D R
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC238265/
https://ncbi.nlm.nih.gov/pubmed/1370083
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