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Immunogenicity and functional characterization of Leishmania-derived hepatitis C virus envelope glycoprotein complex

Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 are the main inducers of a cross-neutralizing antibody response which plays an important role in the early phase of viral infection. Correctly folded and immunologically active E1E2 complex can be expressed in mammalian cells, though the produ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Grzyb, Katarzyna, Czarnota, Anna, Brzozowska, Agnieszka, Cieślik, Anna, Rąbalski, Łukasz, Tyborowska, Jolanta, Bieńkowska-Szewczyk, Krystyna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969751/
https://ncbi.nlm.nih.gov/pubmed/27481352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30627
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