Prognostic impact of mutation profiling in patients with stage II and III colon cancer

Development of colorectal cancer (CRC) associates with accumulation of genetic mutations include the epidermal growth factor receptor (EGFR) signaling pathway. However, whether mutations in KRAS together with downstream factors BRAF, PIK3CA and NRAS impact prognosis is still unclear for stage II-III...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Shen, Yinchen, Han, Xiaohong, Wang, Jianfei, Wang, Shuai, Yang, Hongying, Lu, Shih-Hsin, Shi, Yuankai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830995/
https://ncbi.nlm.nih.gov/pubmed/27074743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24310
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