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Prognostic impact of mutation profiling in patients with stage II and III colon cancer

Development of colorectal cancer (CRC) associates with accumulation of genetic mutations include the epidermal growth factor receptor (EGFR) signaling pathway. However, whether mutations in KRAS together with downstream factors BRAF, PIK3CA and NRAS impact prognosis is still unclear for stage II-III...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shen, Yinchen, Han, Xiaohong, Wang, Jianfei, Wang, Shuai, Yang, Hongying, Lu, Shih-Hsin, Shi, Yuankai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830995/
https://ncbi.nlm.nih.gov/pubmed/27074743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24310
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