Prognostic impact of mutation profiling in patients with stage II and III colon cancer

Development of colorectal cancer (CRC) associates with accumulation of genetic mutations include the epidermal growth factor receptor (EGFR) signaling pathway. However, whether mutations in KRAS together with downstream factors BRAF, PIK3CA and NRAS impact prognosis is still unclear for stage II-III...

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Pubblicato in:Sci Rep
Autori principali: Shen, Yinchen, Han, Xiaohong, Wang, Jianfei, Wang, Shuai, Yang, Hongying, Lu, Shih-Hsin, Shi, Yuankai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830995/
https://ncbi.nlm.nih.gov/pubmed/27074743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24310
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