Prognostic impact of mutation profiling in patients with stage II and III colon cancer

Development of colorectal cancer (CRC) associates with accumulation of genetic mutations include the epidermal growth factor receptor (EGFR) signaling pathway. However, whether mutations in KRAS together with downstream factors BRAF, PIK3CA and NRAS impact prognosis is still unclear for stage II-III...

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Publicat a:Sci Rep
Autors principals: Shen, Yinchen, Han, Xiaohong, Wang, Jianfei, Wang, Shuai, Yang, Hongying, Lu, Shih-Hsin, Shi, Yuankai
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830995/
https://ncbi.nlm.nih.gov/pubmed/27074743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24310
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