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Failure of the Nemo Trial: Bumetanide Is a Promising Agent to Treat Many Brain Disorders but Not Newborn Seizures

The diuretic bumetanide failed to treat acute seizures due to hypoxic ischemic encephalopathy (HIE) in newborn babies and was associated with hearing loss (NEMO trial, Pressler et al., 2015). On the other hand, clinical and experimental observations suggest that the diuretic might provide novel ther...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Ben-Ari, Yehezkel, Damier, Philippe, Lemonnier, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830840/
https://ncbi.nlm.nih.gov/pubmed/27147965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00090
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