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Bumetanide for autism: more eye contact, less amygdala activation

We recently showed that constraining eye contact leads to exaggerated increase of amygdala activation in autism. Here, in a proof of concept pilot study, we demonstrate that administration of bumetanide (a NKCC1 chloride importer antagonist that restores GABAergic inhibition) normalizes the level of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hadjikhani, Nouchine, Åsberg Johnels, Jakob, Lassalle, Amandine, Zürcher, Nicole R., Hippolyte, Loyse, Gillberg, Christopher, Lemonnier, Eric, Ben-Ari, Yehezkel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827728/
https://ncbi.nlm.nih.gov/pubmed/29483603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21958-x
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