Failure of the Nemo Trial: Bumetanide Is a Promising Agent to Treat Many Brain Disorders but Not Newborn Seizures

The diuretic bumetanide failed to treat acute seizures due to hypoxic ischemic encephalopathy (HIE) in newborn babies and was associated with hearing loss (NEMO trial, Pressler et al., 2015). On the other hand, clinical and experimental observations suggest that the diuretic might provide novel ther...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Ben-Ari, Yehezkel, Damier, Philippe, Lemonnier, Eric
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830840/
https://ncbi.nlm.nih.gov/pubmed/27147965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00090
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