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Treatment of NRAS-Mutant Melanoma
NRAS mutations in codons 12, 13, and 61 arise in 15–20 % of all melanomas. These alterations have been associated with aggressive clinical behavior and a poor prognosis. Until recently, there has been a paucity of promising genetically targeted therapy approaches for NRAS-mutant melanoma (and RAS-mu...
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| Pubblicato in: | Curr Treat Options Oncol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4830486/ https://ncbi.nlm.nih.gov/pubmed/25796376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11864-015-0330-z |
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