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MEK inhibitors for the treatment of NRAS mutant melanoma

Melanoma is increasing rapidly in incidence and prevalence, especially in younger females and older males. Treatment options have expanded beyond high-dose interleukin 2 and adoptive T-cell therapy to include inhibitors of immune checkpoints programmed death 1 (PD-1) and cytotoxic T-lymphocyte-assoc...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Main Authors: Sarkisian, Saro, Davar, Diwakar
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108333/
https://ncbi.nlm.nih.gov/pubmed/30154648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S131721
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