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Nucleobase Rec ognition By Truncated α-Hemolysin Pores

The α-hemolysin (αHL) protein nanopore has been investigated previously as a base detector for the strand sequencing of DNA and RNA. Recent findings have suggested that shorter pores might provide improved base discrimination. New work has also shown that truncated-barrel mutants (TBM) of αHL form f...

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Библиографические подробности
Опубликовано в: :ACS Nano
Главные авторы: Ayub, Mariam, Stoddart, David, Bayley, Hagan
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830132/
https://ncbi.nlm.nih.gov/pubmed/26114210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn5060317
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