Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia

BACKGROUND: The constitutive hyper-activation of phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathways has frequently been associated with acute myeloid leukemia (AML). While many inhibitors targeting these pathways have been developed, t...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:J Hematol Oncol
Glavni autori: Gao, Yanan, Gao, Juan, Li, Minghao, Zheng, Yawei, Wang, Yajie, Zhang, Hongyan, Wang, Weili, Chu, Yajing, Wang, Xiaomin, Xu, Mingjiang, Cheng, Tao, Ju, Zhenyu, Yuan, Weiping
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830070/
https://ncbi.nlm.nih.gov/pubmed/27071307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0264-3
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items