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Third-generation inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancer
The tyrosine kinase inhibitors (TKI) against epidermal growth factor receptor (EGFR) are widely used in patients with non-small cell lung cancer (NSCLC). However, EGFR T790M mutation leads to resistance to most clinically available EGFR TKIs. Third-generation EGFR TKIs against the T790M mutation hav...
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Publicado no: | J Hematol Oncol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4830020/ https://ncbi.nlm.nih.gov/pubmed/27071706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0268-z |
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