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Ectopic expression of a small cell lung cancer transcription factor, INSM1 impairs alveologenesis in lung development

BACKGROUND: Insulinoma associated-1 (INSM1) gene is expressed exclusively in early embryonic neuroendocrine tissues, but has been found highly re-activated in most of the neuroendocrine tumors including small cell lung carcinoma. METHODS: In order to elucidate the functional effects of INSM1 in norm...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Chen, Chiachen, Breslin, Mary B., Lan, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830008/
https://ncbi.nlm.nih.gov/pubmed/27072116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-016-0215-3
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