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Functional role of an islet transcription factor, INSM1/IA-1, on pancreatic acinar cell trans-differentiation
In this study, the functional role of INSM1 is examined with an AR42J acinar cell model for trans-differentiation into insulin-positive cells. Islet transcription factors (ITFs: INSM1, Pdx-1, and NeuroD1) are over-expressed in AR42J cells using adenoviral vectors. Addition of Ad-INSM1 alone or the c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3224187/ https://ncbi.nlm.nih.gov/pubmed/21830214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22982 |
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