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T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number
Crucial roles for T-box3 in development are evident by severe limb malformations and other birth defects caused by T-box3 mutations in humans. Mechanisms whereby T-box3 regulates limb development are poorly understood. We discovered requirements for T-box at multiple stages of mouse limb development...
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| Publicado en: | eLife |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4829432/ https://ncbi.nlm.nih.gov/pubmed/27046536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07897 |
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