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A cytosolic protein factor from the naked mole-rat activates proteasomes of other species and protects these from inhibition
The naked mole-rat maintains robust proteostasis and high levels of proteasome-mediated proteolysis for most of its exceptional (~31y) life span. Here, we report that the highly active proteasome from the naked mole-rat liver resists attenuation by a diverse suite of proteasome-specific small molecu...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4829350/ https://ncbi.nlm.nih.gov/pubmed/25018089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.07.005 |
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