Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative Stress

Accumulating evidence indicates that angiotensin-converting enzyme 2 (ACE2) plays a critical role in cardiovascular homeostasis, and its altered expression is associated with major cardiac and vascular disorders. The aim of this study was to evaluate the regulation of vascular function and assess th...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Rabelo, Luiza A., Todiras, Mihail, Nunes-Souza, Valéria, Qadri, Fatimunnisa, Szijártó, István András, Gollasch, Maik, Penninger, Josef M., Bader, Michael, Santos, Robson A., Alenina, Natalia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829150/
https://ncbi.nlm.nih.gov/pubmed/27070147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150255
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