Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative Stress

Accumulating evidence indicates that angiotensin-converting enzyme 2 (ACE2) plays a critical role in cardiovascular homeostasis, and its altered expression is associated with major cardiac and vascular disorders. The aim of this study was to evaluate the regulation of vascular function and assess th...

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Опубликовано в: :PLoS One
Главные авторы: Rabelo, Luiza A., Todiras, Mihail, Nunes-Souza, Valéria, Qadri, Fatimunnisa, Szijártó, István András, Gollasch, Maik, Penninger, Josef M., Bader, Michael, Santos, Robson A., Alenina, Natalia
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829150/
https://ncbi.nlm.nih.gov/pubmed/27070147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150255
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