Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative Stress

Accumulating evidence indicates that angiotensin-converting enzyme 2 (ACE2) plays a critical role in cardiovascular homeostasis, and its altered expression is associated with major cardiac and vascular disorders. The aim of this study was to evaluate the regulation of vascular function and assess th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rabelo, Luiza A., Todiras, Mihail, Nunes-Souza, Valéria, Qadri, Fatimunnisa, Szijártó, István András, Gollasch, Maik, Penninger, Josef M., Bader, Michael, Santos, Robson A., Alenina, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829150/
https://ncbi.nlm.nih.gov/pubmed/27070147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150255
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