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STRUCTURE/FUNCTION MAPPING OF AMINO ACIDS IN THE N-TERMINAL ZINC FINGER OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 NUCLEOCAPSID PROTEIN: RESIDUES RESPONSIBLE FOR NUCLEIC ACID HELIX DESTABILIZING ACTIVITY()
The nucleocapsid protein (NC) of HIV-1 is 55 amino acids in length and possesses two CCHC-type zinc fingers. Finger one (N-terminal) contributes significantly more to helix destabilizing activity than finger two (C-terminal). Five amino acids differ between the two zinc fingers. To determine at the...
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| Publié dans: | Biochemistry |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4829079/ https://ncbi.nlm.nih.gov/pubmed/17029416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060925c |
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