STRUCTURE/FUNCTION MAPPING OF AMINO ACIDS IN THE N-TERMINAL ZINC FINGER OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 NUCLEOCAPSID PROTEIN: RESIDUES RESPONSIBLE FOR NUCLEIC ACID HELIX DESTABILIZING ACTIVITY()

The nucleocapsid protein (NC) of HIV-1 is 55 amino acids in length and possesses two CCHC-type zinc fingers. Finger one (N-terminal) contributes significantly more to helix destabilizing activity than finger two (C-terminal). Five amino acids differ between the two zinc fingers. To determine at the...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Narayanan, Nirupama, Gorelick, Robert J., DeStefano, Jeffrey J.
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829079/
https://ncbi.nlm.nih.gov/pubmed/17029416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060925c
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