Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection

Recent successes with monoclonal antibody cocktails ZMapp(TM) and MIL77 against Ebola virus (EBOV) infections have reignited interest in antibody-based therapeutics. Since the production process for monoclonal antibodies can be prolonged and costly, alternative treatments should be investigated. We...

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發表在:Sci Rep
Main Authors: Zheng, Xuexing, Wong, Gary, Zhao, Yongkun, Wang, Hualei, He, Shihua, Bi, Yuhai, Chen, Weijin, Jin, Hongli, Gai, Weiwei, Chu, Di, Cao, Zengguo, Wang, Chong, Fan, Quanshui, Chi, Hang, Gao, Yuwei, Wang, Tiecheng, Feng, Na, Yan, Feihu, Huang, Geng, Zheng, Ying, Li, Nan, Li, Yuetao, Qian, Jun, Zou, Yong, Kobinger, Gary, Gao, George Fu, Qiu, Xiangguo, Yang, Songtao, Xia, Xianzhu
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828711/
https://ncbi.nlm.nih.gov/pubmed/27067649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24179
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